Webb1 juni 2013 · 1. Introduction. The Thy-1-integrin interaction, initially described to mediate neuron–astrocyte communication [1], has set the basis for various reports showing interactions in Trans of Thy-1 with integrin receptors containing β 2 or β 3 subunits [2].Indeed, Thy-1 interacts with α X β 2 integrin, an integrin highly expressed on the … Webb15 okt. 2010 · In contrast, none of the tumor cell lines expressed the other known ligand of Thy1, integrin alpha M/CD11b (Fig. 4 E). These results indicate that tumor-associated lymphatic vessels express high levels of Thy1 and that they might interact with tumor cells via Thy1 to serve as conduits for tumor metastasis to the sentinel lymph nodes.
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Webb7 apr. 2024 · There are many reports of THY1-147 associated functions in different cellular settings, most of them describing CD90 as 148 the modulator of integrin signalling (in trans or in cis). Many of the integrin-CD90 and 149 syndecan-4-CD90 interaction studies have identified the signalling being induced in 150 the integrin and syndecan-4 … Webb27 juni 2024 · Thy-1 downregulation, integrin β3 upregulation and autophagy inhibition were also detected in a mouse model of LPS-induced pulmonary fibrosis, which could be … bryant myers album
Soluble Thy-1 reverses lung fibrosis via its integrin-binding motif
The function of Thy-1 has not yet been fully elucidated. It has speculated roles in cell-cell and cell-matrix interactions, with implication in neurite outgrowth, nerve regeneration, apoptosis, metastasis, inflammation, and fibrosis. The Thy-1 knockout (KO) mice are viable and appear grossly normal. They display normal social interactions and normal learning in a maze, but fail to learn from social cues (e.g. learning from … Webb15 feb. 2024 · The preferential enhancement of MSC functions in the CD34 + THY1 + subset may provide a new treatment strategy for regenerating damaged bone/cartilage in arthritic joints. Background In rheumatoid arthritis (RA) and osteoarthritis (OA), the joint function is impaired due to cartilage and bone damage. Webb21 mars 2024 · THY1 (Thy-1 Cell Surface Antigen) is a Protein Coding gene. Diseases associated with THY1 include Retinal Artery Occlusion and Thymoma . Among its … examples of zero polynomials